• Production of reactive oxygen species ROS during RSV

  2025-01-09

  

  Production of reactive oxygen species (ROS) during RSV infection is one the important ways that neutrophils can injure the lungs [2], [24], [25]. Lipoxygenases are considered as an important source of producing ROS inside the glycogen phosphorylase [26]. Several studies have indicated that the 12/1

• br Materials and Methods br Results

  2025-01-09

  

  Materials and Methods Results Discussion 15-HETE is a predominant eicosanoid in pulmonary vascular remodeling, and it could promote hypoxia-induced PAH via its involvement in the regulation of proliferation and cell cycle progression in PASMCs. To understand its role in HPH, we have previou

• Protein phosphorylation is an important posttranslational me

  2025-01-09

  

  Protein phosphorylation is an important posttranslational mechanism for the regulation of distribution, trafficking, and function of modified proteins (Wang et al., 2014). GluA1 phosphorylation at S845 also has functional consequences (Lu and Roche, 2012). For instance, S845 phosphorylation drove tr

• GABAB receptor is associated with brain

  2025-01-09

  

  GABAB receptor is associated with Methyl violet 10B stain and behavioral diseases, including epilepsy, spasticity, anxiety and neuropathic pain (Bettler et al., 2004, Bowery et al., 2002, Froestl, 2010). Baclofen, a clinical drug and selective GABAB receptor agonist, is used to treat muscle spastic

• This study evaluated the anti tumor influences of LA

  2025-01-09

  

  This study evaluated the anti-tumor influences of LA against HepG2 Bone histology stain in vivro, and investigated the molecular mechanisms of inducing apoptosis. Overall, our studies suggested that LA is a promising anti-cancer drug and a possible novel therapeutic agent directed toward the mitoch

• Vascular interventional radiology VIR laboratories perform

  2025-01-09

  

  Vascular interventional radiology (VIR) laboratories perform a myriad of procedures ranging from simple tunneled peripherally inserted central catheter lines to complex transjugular intrahepatic portosystemic shunt placements. Infections are a common complication in the VIR environment; thus, the pr

• However a high triglyceride level was

  2025-01-09

  

  However, a high triglyceride level was associated with dementia in a study with subjects aged ≥65 years (Raffaitin et al., 2009). In another study, the serum triglyceride levels of three different transgenic mouse strains mimicking AD were also evaluated within the progression of the pathology. In o

• br Expression of adiponectin mRNA in chickens We first sough

  2025-01-08

  

  Expression of adiponectin mRNA in chickens We first sought to determine the nucleotide sequence of the chicken adiponectin cDNA. The open reading frame of the chicken adiponectin cDNA consists of 735 nucleotides that was 65–68% homologous to various mammalian adiponectin cDNAs (Maddineni et al.,

• To assess relative metabolic activity and proliferation of c

  2025-01-08

  

  To assess relative metabolic activity and proliferation of Cy5 streptavidin probe attached to various substrates we used the MTT assay [29], [30]. In order to compare the metabolic activity of cells under the various conditions irrespective of the number or viability of the cells, we performed a Pi

• SU(VAR)3-9 inhibitor br Introduction br Rac dependent ROS an

  2025-01-07

  

  Introduction Rac1-dependent ROS and SU(VAR)3-9 inhibitor regulation in neuronal functions NOX-mediated ROS have an important role as physiological messengers. One remarkable example regarding such a function is during axonal formation. In this line, increased p40phox/NOX2 levels and co-localiz

• Mushroom poisoning research br Experimental Procedures br Ac

  2025-01-07

  

  Experimental Procedures Acknowledgments Introduction Synapses are fundamental units for efficient communication between neurons and their target cells. Despite significant progress in understanding the structure of matured synapses, less is known about the mechanisms by which neurotransmitt

• br Conflict of interest statement br

  2025-01-07

  

  Conflict of interest statement Benign prostatic hyperplasia (BPH) is a highly complex process characterized by an increased number of epithelial and stromal RO-3 in the transition zone. , , Autopsy studies by McNeal detail the evolution of histological changes within these 2 cellular compartmen

• However there are studies revealing the dark side

  2025-01-06

  

  However, there are studies revealing the “dark side” of autophagy at later stages in cancers, when oncogenes (mainly K-ras and B-raf) are activated and/or tumour suppressors such as PTEN and p53 are inactivated. These studies are based on the use of GEMM and deletions of essential autophagy genes (A

• br Results br Discussion ER and GR

  2025-01-06

  

  Results Discussion ER and GR play opposite phenotypic roles in the normal endometrium, with ER promoting growth and GR inhibiting growth. Here, we show that in endometrial cancer, GR expression is associated with worse outcomes and higher-grade tumors, and this association is observed only in

• br Results br Discussion Dopamine regulates behavioral respo

  2025-01-04

  

  Results Discussion Dopamine regulates behavioral responses to nicotine in Drosophila (Bainton et al., 2000), but neurochemical measurements of dopamine after nicotine stimulation had not been made. Here, we demonstrate for the first time that the stimulation of nAChRs causes dopamine release i

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