Archives
- 2018-07
- 2018-10
- 2018-11
- 2019-04
- 2019-05
- 2019-06
- 2019-07
- 2019-08
- 2019-09
- 2019-10
- 2019-11
- 2019-12
- 2020-01
- 2020-02
- 2020-03
- 2020-04
- 2020-05
- 2020-06
- 2020-07
- 2020-08
- 2020-09
- 2020-10
- 2020-11
- 2020-12
- 2021-01
- 2021-02
- 2021-03
- 2021-04
- 2021-05
- 2021-06
- 2021-07
- 2021-08
- 2021-09
- 2021-10
- 2021-11
- 2021-12
- 2022-01
- 2022-02
- 2022-03
- 2022-04
- 2022-05
- 2022-06
- 2022-07
- 2022-08
- 2022-09
- 2022-10
- 2022-11
- 2022-12
- 2023-01
- 2023-02
- 2023-03
- 2023-04
- 2023-05
- 2023-06
- 2023-07
- 2023-08
- 2023-09
- 2023-10
- 2023-11
- 2023-12
- 2024-01
- 2024-02
- 2024-03
- 2024-04
- 2024-05
- 2024-06
- 2024-07
- 2024-08
- 2024-09
- 2024-10
- 2024-11
- 2024-12
- 2025-01
- 2025-02
-
br Experimental Procedures br Acknowledgments br Introductio
2018-10-24
Experimental Procedures Acknowledgments Introduction Master transcription regulators control the pluripotent gene expression in embryonic stem buy Lomefloxacin HCl (ESCs) (Avilion et al., 2003; Chambers et al., 2003; Mitsui et al., 2003; Nichols et al., 1998). X chromosome inactivation (XCI
-
We have developed a protocol for the
2018-10-24
We have developed a protocol for the efficient differentiation of functional HLCs from hPSCs that does not require the addition of recombinant growth factors and is applicable to both hESCs and hiPSCs. During the development of the protocol, it came as a surprise to discover that pluripotent p38 inh
-
br Materials and methods br Results br Discussion
2018-10-24
Materials and methods Results Discussion NPY is one of the most common neuropeptides in mammals, and it is abundant in the central and peripheral nervous system. Recent studies have indicated that the neuropeptides SP and NPY can regulate many biological activities in BMSCs and MC3T3 sodium
-
Introduction Induced pluripotent stem cells iPSCs
2018-10-24
Introduction Induced pluripotent stem leukotriene receptor antagonists (iPSCs) are stem cells generated by artificial reprogramming of somatic cells with defined factors, such as Oct4, Sox2, Klf4, and c-Myc (Takahashi and Yamanaka, 2006), which are supplied to target cells by exogenous gene expres
-
br Experimental Procedures br Acknowledgments
2018-10-24
Experimental Procedures Acknowledgments Introduction Hematopoietic stem ambroxol hydrochloride (HSCs) are capable of both self-renewal and production of mature blood lineages. Players in this balanced regulation include transcription factors, cell-cycle regulators, signaling molecules, surf
-
br Experimental Procedures br Author Contributions br Acknow
2018-10-24
Experimental Procedures Author Contributions Acknowledgments We thank Cory Abate-Shen, Maho Shibata, and Flaminia Talos for insightful comments on the manuscript. This work was supported by NIHR01DK076602. A.M. and R.T. were supported by post-doctoral fellowships from the DOD Prostate Cance
-
We obtained some evidence that NMD not
2018-10-24
We obtained some evidence that NMD not only influences hESC fate through TGF-β and BMP signaling, but also through the WNT, FGF, and NOTCH pathways (Figure 2E). This raises the possibility that the ability of NMD to influence Anti-cancer Compound Library and mesoderm differentiation is a combinator
-
At a global level the analysis of DNA
2018-10-24
At a global level, the analysis of DNA-methylation profiles provides important insights into molecular and cell growth characteristics of PSC that would otherwise be difficult to identify. Reprogramming-associated variations in X-linked CpG methylation is of particular interest because of the comple
-
Noticeably the redistribution of protein from
2018-10-24
Noticeably, the redistribution of protein from the cytoplasm to the nucleus was observed in many regulatory molecules, such as nuclear factor κB (Haddad, 2009) and AKT (Xuan et al., 2006). We thus speculated that the increased nuclear MIF in hypoxic tumors may interact with the transcription factors
-
Impaired neural migration and defects
2018-10-24
Impaired neural migration and defects in the selective serotonin reuptake inhibitor cytoskeleton are well-known factors contributing to malformations during the cortical development (Pang et al., 2008). Reduced expression of NSUN2 in human NES cells impaired migration toward the chemoattractant FGF
-
br Results br Discussion We have developed
2018-10-24
Results Discussion We have developed an optimized and streamlined method for efficient engineering of targeted chromosomal translocations in human MSCs and iPSCs. We first generated an all-in-one plasmid system to co-express two sgRNAs, the Streptococcus pyogenes Cas9 flanked by two NLSs and a
-
These organoid technologies have been pioneered for the smal
2018-10-24
These organoid technologies have been pioneered for the small intestine (Sato et al., 2009) and later extended also to other organs or parts of organs (Nakano et al., 2012). Recently, protocols for the generation of human brain-like organoids have been developed, including protocols for cerebral (La
-
The solids refractive index is primarily specified by its ch
2018-10-24
The solids refractive index is primarily specified by its chemical composition. Indeed, a comparison between these indicators for the films of TiO2 and TiO2–CdO with the uniform thickness shows that the former is of higher value than the latter (1.97 against 1.91 [15]). However, the refractive index
-
x y is a polynomial of
2018-10-24
(x, y) is a polynomial of a finite degree k, and S(x, y) is an arbitrary harmonic function,. In order to construct spectrographic media, we need homogeneous polynomials, and they can be expressed as a sum of terms . Then let us put and calculate Δg: It is clear that the polynomial with a degre
-
Let us examine a thermodynamic model taking into account
2018-10-24
Let us examine a thermodynamic model taking into account the influence of interfacial tension on the reconstructive phase transition. Let us analyze an idealized case when the polycrystalline sample consists of spherical particles of radius R. Let us designate the Gibbs free Zebularine in the low-t
16383 records 1087/1093 page Previous Next First page 上5页 10861087108810891090 下5页 Last page