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MCs play a key role in the
2019-04-19
MCs play a key role in the maintaining homeostasis of tissues where they reside by participating in tissue repair, reactions against viral and parasitic infections, and aiding in the regulation of various cell types such as dendritic cells, T cells, and macrophages. In addition, MCs are involved in
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Long marginalised as a disorder confined
2019-04-19
Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th
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br Materials and methods br Results br Discussion br Conclus
2019-04-18
Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential AM966 (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation [1–4]. However, in
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CT analysis of tumour bearing bones showed
2019-04-18
μCT analysis of tumour bearing bones showed significantly increased bone density in animals receiving zoledronic acid, alone or in combination with doxorubicin, compared to PBS control. Our results confirmed that a single dose of zoledronic 2-deoxy-d-glucose caused sustained bone effects throughout
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TCEP manufacturer The review Bile acid receptor link nutrien
2019-04-18
The review “Bile TCEP manufacturer receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides are non-toxic, bu
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Pharmacokinetics analysis of AT on SCID mice
2019-04-17
Pharmacokinetics analysis of AT-406 on SCID mice bearing MDA-MB-231 tumors has shown that AT-406 achieves a maximum concentration in plasma between 1.5μM and 9.9μM, and a maximum concentration in tumor tissue between 0.5μM and 18.2μM, depending on the dose and administration route (intravenous versu
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Most forms of AVNRT are created by reentry between
2019-04-17
Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer
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Of special note Abcg g has been
2019-04-17
Of special note, Abcg5/g8 has been identified as Lith9 by QTL studies in mice. As shown in Fig. 4, Lith9 is localized on mouse chromosome 17 and is co-localized with a genetic biomarker D17Mit155 at approximately 55 centimorgans (cM). In the Lith9 QTL region, Abcg5/g8 is a strong candidate for this
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The goals of Vision the
2019-04-17
The goals of Vision 2020—the global initiative to eliminate avoidable blindness by 2020—include increasing cataract surgical rate and cataract surgical coverage. However, quality must not be sacrificed for quantity. The final visual outcome matters, both to the individual patient and to the communit
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br A tactical change in research and
2019-04-17
A tactical change in research and advocacy is needed urgently before mental health services will be made a priority in low-income and middle-income countries. Mental disorders and substance misuse are the greatest contributors to the global burden of disability, with 175·3 million years lost to di
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La incorporaci n de los atributos culturales asociados a la
2019-04-17
La incorporación de los atributos culturales asociados concentration calculator la población indígena en las instituciones religiosas, entre ellos el idioma, fue de vital importancia en el desarrollo, especialmente dinámico a partir de los años cincuenta del siglo xx en distintas instituciones de in
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In advanced GIST patients where a
2019-04-17
In advanced GIST patients where a course of treatment of Imatinib is interrupted by disease progression, subsequent rechallenge with Imatinib restored tumor control in most patients. In the prospective BFR14 trial, 25 patients with disease progression after interruption of one year of treatment rest
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A number of clinical studies have confirmed the
2019-04-17
A number of clinical studies have confirmed the beneficial effect of ranolazine in either prevention or treatment of AF. The first strong evidence was provided by MERLIN-TIMI 36 trial [the Metabolic Efficiency With Ranolazine for Less Ischemia in Non–ST-Elevation Acute Coronary Syndrome–Thrombolysis
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Era tal el recelo que hab a sobre el
2019-04-17
Era tal el recelo que había sobre el enriquecimiento de los ministros que en enero de 1622 se intentó investigar los orígenes de su riqueza. El mismo mes se publicó un decreto que estipulaba que todos los que habían tenido cargos alk pathway partir de 1592 debían inventariar sus propiedades ante un
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retinoid x receptor br The Ministerial Conference on in Asia
2019-04-17
The Ministerial Conference on in Asia and the Pacific is taking place on Nov 24–28, 2014, in Bangkok, Thailand. In recognition of this and parallel plans from the UN Economic Commission for Africa for a Ministerial Conference on CRVS for African countries, to be held in Côte d\'Ivoire in February
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