• In silico prediction software SIFT PolyPhen CADD and other

  2019-05-05

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

• Respecto a la ideolog a que

  2019-05-05

  

  Respecto Mitiglinide Calcium la ideología que ostentó en los años ochenta, temporalidad en que fue ajusticiado el coronel Máximo Zepeda, podemos decir que ésta se fue matizando durante su larga trayectoria periodística hasta su decadencia financiera y posterior desaparición, la que fue examinada por

• br Materials and methods br Results br Discussion Osteosarco

  2019-05-04

  

  Materials and methods Results Discussion Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common type of primary bone malignancy [20]. Over the past few decades, the introduction of combinatorial chemotherapy has improved the 5-year overall survival rate of

• More recently primary tumor driven

  2019-05-04

  

  More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i

• It is in this context that the recent

  2019-05-04

  

  It is in this context, that the recent study of Matsuyama et al. sheds further light on the relationships between histoanatomy and atrial arrhythmogenesis . This investigation used high-density optical mapping to study atrial flutter/atrial fibrillation in isolated rat hearts . Atrial arrhythmia wa

• Since many decades bone tumours have stimulated imagination

  2019-05-04

  

  Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh

• Further complicating matters is that although menopause can

  2019-05-04

  

  Further complicating matters is that although menopause can increase serum BTMs, other normal physiological conditions, certain disease states, and drugs are also associated with elevated BTM concentrations [81–83]. Low body-mass index (BMI) is a risk factor for low bone density [84] and evidence ha

• Early repolarization ER is characterized

  2019-05-04

  

  Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor

• Como ha destacado Leonardo Tarife o su

  2019-05-04

  

  Como ha destacado Leonardo Tarifeño, “su obra nace de un malestar con el mundo que se estetiza para revelarse, y en ningún caso para ocultarse o refinarse” (75). Este malestar, aunado al afán realista localizable en su trabajo produce una búsqueda de elementos para acercar al lector con diversas fac

• br In their policy analysis Yusra Ribhi Shawar and colleague

  2019-05-04

  

  In their policy analysis, Yusra Ribhi Shawar and colleagues (August, 2015) outline the complex responses needed to make surgery a global health priority, highlighting as a major challenge that “consensus needs to be reached on solutions”. Professional interests might have forestalled consensus on

• En M xico el folclor nacionalista

  2019-05-04

  

  En México, el folclor nacionalista de los siglos xix y xx matizó la tipificada creencia cultural de la “convivencia natural” del mexicano con la muerte para explicar y sobrellevar, incluso de manera socarrona, los estragos económicos y sociales del destino mexicano. Elsa Malvido, en este sentido, en

• br Ogolpe militar do dia de setembro de

  2019-05-04

  

  Ogolpe militar do dia 11 de setembro de 1973, no Chile, destituiu do poder o então presidente Salvador Allende, eleito em 1970 pela Unidad Popular (up), coalizão política composta por partidos de esquerda que propunham entacapone “via chilena para o socialismo”. De acordo com Priscila Carlos Brand

• De ser posible esta marcaci n temporal no se correr

  2019-05-04

  

  De ser posible esta marcación temporal, ¿no se correría el riesgo de fragmentar el pensamiento del autor? Por el contrario, si se contemplara todo el contenido de las obras de Morin con sus ideas de la complejidad, ¿no se asumiría el riesgo de globalizar y forzar su pensamiento? El propio Morin se h

• This study was supported by the Ministry of Education

  2019-05-04

  

  This study was supported by the Ministry of Education, Science and Technological Development of Serbia (grant# 175083). Introduction In the United States, PCa was the most commonly found cancer among all males, according to the US Centers for Disease Control and Prevention (CDC). In Taiwan, PCa

• br Discussion In this study AT originated in

  2019-05-04

  

  Discussion In this study, AT originated in the orifice of the RAA in a patient with ARVC/D. The origins of these ATs were quite close, which is supported by similar P-wave morphology of each AT. The ATs could be ablated by multiple endocardial RF applications. In this case, the exact mechanism un

16460 records 1065/1098 page Previous Next First page 上5页 10611062106310641065 下5页 Last page