• p2y inhibitor In addition to inducing IKs dysfunction throug

  2019-05-13

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• Social determinants are the lived conditions

  2019-05-13

  

  Social determinants are the lived conditions (ie, social and economic) that influence wellbeing, and environmental influences on behaviour are those assessed with the health behaviour theory. Stages of change models (ie, those that recognise health behaviour as a series of progressive steps leading

• Almost all men are eligible to have

  2019-05-13

  

  Almost all men are eligible to have a vasectomy. It is highly effective, convenient, and easy to provide, and is also, along with female sterilisation, one of only two permanent methods of contraception. For these reasons, and to share contraceptive responsibilities, kit inhibitor is widely chosen i

• zolmitriptan Despertar de la ilusi n le significa a Villoro

  2019-05-13

  

  Despertar de la “ilusión” le significa zolmitriptan Villoro su tránsito a la crítica de las filosofías de J. Rawls yJ. Habermas, afirma que no son pertinentes para el caso de nuestra condición social y política, ya que a pesar de las diferencias importantes entre sus teorías, ambas parten “de la ide

• years ago published a groundbreaking and taboo breaking

  2019-05-13

  

  5 years ago, published a groundbreaking (and taboo-breaking) Series on stillbirths. Its powerful mix of advocacy and hard data attracted more media attention than perhaps any other Series, and made waves on numerous levels, from the individual to the intergovernmental. Working closely with countrie

• br In the past decade Brazil has achieved considerable

  2019-05-13

  

  In the past decade, Brazil has achieved considerable progress in malaria control, with 140 000 cases reported in 2015, the lowest numbers since 1980. Part of this success has been attributed to the establishment of a large network of around 3000 diagnostic and treatment units for malaria. A remark

• Clearly there are limitations to

  2019-05-10

  

  Clearly there are limitations to the current study. These include the single centre, retrospective nature of the study as well as its relatively small sample size compared with the randomised data. However, the duration of follow up is considerably longer than these trials (Table 1). In conclusion,

• Bien templada en fin entre sus numerosas fuentes de conocimi

  2019-05-10

  

  Bien templada, en fin, entre sus numerosas fuentes de conocimiento, sor Juana es tan pitagórica como san Agustín, Boecio o Gaffurio; foguea su neoplatonismo en ideas de Sinesio, Jámblico o Ficino, y voltage gated potassium channel la vez está en posibilidad de compulsar sus adquisiciones teóricas so

• In Grabowski and colleagues report that

  2019-05-10

  

  In , Grabowski and colleagues report that women consistently using DMPA were at nearly double the risk of acquiring herpes simplex virus type 2 (HSV2) compared with those using no contraception; in a sensitivity analysis limited to those whose main partner had HSV2, the risk increased by six times.

• Sin embargo la Relaci n

  2019-05-10

  

  Sin embargo, la Relación no fue traducida en forma igualmente precisa por Ulloa, que nos devuelve un texto corrompido, lo cual se manifiesta en las transcripciones de los términos en la lengua indígena. Por fortuna, es posible comparar el texto italiano con otras versiones producidas durante la prim

• El Grounded Theory permite un an lisis

  2019-05-10

  

  El Grounded Theory permite un análisis mucho más profundo y cualitativo de estos textos constitucionales. Si además los concebimos como “narrativas constitucionales”, escritas por muchas manos (los participantes directos o indirectos de las Asambleas Constituyentes) con la pretensión de definir el s

• En el primer apartado presentamos

  2019-05-10

  

  En el primer apartado, presentamos las modificaciones que se produjeron en los lineamentos que proponen estos organismos para la política social de la región y buscaremos mostrar que ocurrió un desplazamiento de la cuestión social entendida como pobreza nae inhibitor su redefinición como desigualdad

• As condi es desta reinser o seriam

  2019-05-10

  

  As condições desta “reinserção” seriam consolidadas influenza m2 protein partir do chamado “autogolpe”, quando Fujimori fechou o congresso e interveio no poder judicial em abril de 1992, decretando à moda argentina um “Gobierno de emergencia y reconstrucción nacional”. Em uma perversão da democracia

• br Results and discussion br

  2019-05-10

  

  Results and discussion Authorship contributions Conflict of interest Acknowledgments This work is supported by grants from the United States National Institutes of Health/National Cancer Institute: R01 CA098472 and R01 CA170334. We thank Dr. Dan Zhang and Andy Awwad for technical assista

• br In a Comment February we argued

  2019-05-10

  

  In a Comment (February, 2017), we argued that action on the conditions currently referred to as non-communicable diseases (NCDs) may be hampered by the inadequacy of their label. We received a remarkable amount of feedback on this suggestion, and in this Comment we synthesise the responses garnere

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