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The majority of studies conducted
2018-11-07
The majority of studies conducted on sleep and cognitive functioning have employed a total sleep deprivation protocol in which participants are typically deprived of one or more nights of sleep. An experimentally induced total sleep deprivation, however, may not accurately resemble the kind of sleep
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Metabotype data coupled to metagenomic measurements
2018-11-07
Metabotype data coupled to metagenomic measurements (information on gut microbiota) can enhance our knowledge about the complex interactions between the host and its gut microbiota (Kaddurah-Daouk et al., 2014) as well as their role in modulating host physiology, gut microbiome-related disorders, an
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br Materials and Methods br Paclitaxel Concentration
2018-11-07
Materials and Methods Paclitaxel Concentration Determination in Cell Pellets and Supernatants Calu-6 cells were treated with 100nM TVB-3166 for 24h or 50nM TVB-3664 for 48h. Paclitaxel was added to the cell culture media to a final concentration of 6nM. After the 2h of incubation with paclitax
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The decrease in blood oxygen saturation correlates with incr
2018-11-07
The decrease in blood oxygen saturation correlates with increased plasma EPO levels in Slc40a1C326S/C326S mice. Hypoxia is the main physiological inducer of EPO production in the kidney via the hypoxia inducible factor HIF2α/HIF1β heterodimer (Haase, 2010). In Slc40a1C326S/C326S mice iron may also d
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NAbs occurring after initial infection with HIV are generall
2018-11-07
NAbs occurring after initial infection with HIV-1 are generally not associated with any clinical or biological benefits. Doria-Rose et al. (2010) suggested that the limited breadth of neutralization observed in whole-serum samples from LTNP patients maybe attributable to low levels of antigenic stim
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br Data sets and attributes The
2018-11-07
Data sets and attributes The data published here are organized in two ‘csv’ files, ‘rawdata.csv.gz’ (4.5MB) and ‘features.csv’ (200kB). The raw data are stored in the first file ‘rawdata.csv.gz’, where each line represents a single measurement per sensor. Consequently, one needs to read specific
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Data experimental design materials and methods
2018-11-07
Data, experimental design, materials and methods Conflict of interest Acknowledgements We would like to acknowledge the BBSRC for support (grant BB/H001948/1), the Chemical Analysis Facility at the University of Reading for access to the Orbitrap instrument, the Centre for Advanced Microscopy
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br Neuroimmune mechanisms underlying sex differences Measuri
2018-11-07
Neuroimmune mechanisms underlying sex differences Measuring developmental and life-long effects of ELA exposure produces a moving baseline from which to gauge anatomical and functional differences. Therefore the addition of sex as a factor in developmental studies is challenging. While some anima
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monocarboxylate transporters Recent research additionally su
2018-11-07
Recent research additionally suggests a crucial role for the BG in filtering information into WM. Evidence for this monocarboxylate transporters comes from several sources. Computational models of WM that model the BG as responsible for selectively updating information in WM reproduce core human WM
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CGP 41251 In adults information converging on hippocampus fr
2018-11-07
In adults, information converging on hippocampus from PRC and PHC via entorhinal cortex [ERC] takes two routes through the HIPP, a short route through the monosynaptic circuit with bidirectional ERC←→CA1 connections and a longer route through the trisynaptic circuit (containing DG, CA3). While the s
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Rate of change maps for measures of apparent
2018-11-07
Rate of change maps for measures of apparent cortical thickness are shown in Fig. 7. Thinning of the order GSK1120212 appears to be present across the entire cortex and across the entire age range from 3 to 21, contrasting with some previous reports of early childhood cortical thickening. If anythin
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Affective memory biases a key element
2018-11-07
Affective memory biases, a key element of the cognitive (Disner et al., 2011) and neuropsychological models of MDD (Roiser and Sahakian, 2013), are a common finding (Dalgleish and Werner-Seidler, 2014; Bradley and Mathews, 1988). Dalgleish and Werner-Seidler (2014) highlight the key components of th
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egfr inhibitors Moreover these findings add to the
2018-11-07
Moreover, these findings add to the body of literature documenting that individuals with ASD and low expressing 5-HTTLPR genotypes exhibit marked differences in egfr inhibitors function in comparison to other groups. Using a sample overlapping with that of the present study, Wiggins and colleagues
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br Livable cities in popular media and global
2018-11-06
Livable cities in popular media and global ranking The term “livable cities” appeared in the popular literature during the 1980s in connection with the growing environmental concerns and the increasing Tubastatin A HCl among world cities to attract foreign investments and boost their economies. T
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Spinal TB has a wide variety of manifestations
2018-11-06
Spinal TB has a wide variety of manifestations, and the infected spinal vertebra causes inflammation and instability, which initially constitutes axial pain. The most common symptom in our patients was back pain (77%) and systemic symptoms such as fever were seldom noticed (8%), which were consisten
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